Is ECMO Ready for the Big Time?
SUMMARY AND COMMENT
Ambitious study, ambiguous result
Reviewing:
Peek GJ et al., Lancet 2009 Sep 16
Zwischenberger JB and Lynch JE., Lancet 2009 Sep 16
Procalcitonin Algorithm Reduces Antibiotic Use for Lower Respiratory Tract Infections
SUMMARY AND COMMENT
Without increasing adverse outcomes of disease
Reviewing:
Schuetz P et al., JAMA 2009 Sep 9; 302:1059
Yealy DM and Fine MJ., JAMA 2009 Sep 9; 302:1115
Cardiac Surgery in Patients with Carotid Stenosis
SUMMARY AND COMMENT
Combining endarterectomy with cardiac surgery did not prevent perioperative strokes.
Reviewing:
Li Y et al., Arch Neurol 2009 Sep; 66:1091
Hepatitis B Guidelines, Updated
CLINICAL PRACTICE GUIDELINE WATCH
This revised document provides useful information about the prevention, diagnosis, and management of HBV infection.
Reviewing:
Lok ASF and McMahon BJ., Hepatology 2009 Sep; 50:661
Coronary Artery Bypass Grafting After Percutaneous Coronary Intervention
SUMMARY AND COMMENT
Findings from a large observational study support the safety of a "PCI first" strategy in many patients.
Reviewing:
Yap C-H et al., JACC Cardiovasc Interv 2009 Aug; 2:758
Mack M., JACC Cardiovasc Interv 2009 Aug; 2:765
Elevated Troponin After Coronary Bypass Surgery: What Does It Mean?
SUMMARY AND COMMENT
Observational findings suggest that very high TnT levels predict adverse outcomes.
Reviewing:
Mohammed AA et al., Circulation 2009 Sep 8; 120:843
Inpatient Surgery and In-Hospital Mortality
SUMMARY AND COMMENT
Hospitals with low and high perioperative death rates have surprisingly similar rates of perioperative complications, which suggests that "failure to rescue" is the primary determinant of in-hospital mortality.
Reviewing:
Ghaferi AA et al., N Engl J Med 2009 Oct 1; 361:1368
Jacobs DO., N Engl J Med 2009 Oct 1; 361:1398
Bortezomib for Systemic Amyloidosis
SUMMARY AND COMMENT
Overall response was achieved by 50% of patients.
Reviewing:
Reece DE et al., Blood 2009 Aug 20; 114:1489
Survival to Discharge After Cardiac Arrest
SUMMARY AND COMMENT
Hospital characteristics explain much of the lower survival rate that was noted for black patients compared with white patients.
Reviewing:
Chan PS et al., JAMA 2009 Sep 16; 302:1195
CT Scanning for Cardiac Sources of Embolism
SUMMARY AND COMMENT
September 29, 2009
Richard T. Lee, MD
Neurology
In patients with recent strokes, cardiac CT using 64-slice technology can detect most of the high-risk cardiac sources of embolism identified by transesophageal echocardiography.
Reviewing:
Hur J et al., Stroke 2009 Jun; 40:2073