Maternal Depression: We Must Be Aware
SUMMARY AND COMMENT
Among women with symptoms of postpartum depression, having a controlling partner was significantly associated with persistent depression.
Reviewing:
Blabey MH et al., Am J Obstet Gynecol 2009 Aug; 201:173.e1
Price of Nonadherence to Antihypertensive Medications
SUMMARY AND COMMENT
High adherers had a significantly lower risk for cardiovascular disease.
Reviewing:
Mazzaglia G et al., Circulation 2009 Oct 20; 120:1598
Chobanian AV., Circulation 2009 Oct 20; 120:1558
Anticholinergic Drugs and Acute Urinary Retention
SUMMARY AND COMMENT
Risk is highest during the first several weeks of treatment.
Reviewing:
Martín-Merino E et al., J Urol 2009 Oct; 182:1442
Work-Hour Limits for Residents — But What About Attendings?
SUMMARY AND COMMENT
Overnight work by attending physicians with <6 hours of sleep was associated with risk for next-day operative complications.
Reviewing:
Rothschild JM et al., JAMA 2009 Oct 14; 302:1565
BP Reduction in Acute Intracranial Hemorrhage: How Low Should We Go?
SUMMARY AND COMMENT
This small phase I study shows that BP reduction is feasible but does not identify an optimum target level.
Reviewing:
Qureshi AI., Crit Care Med 2009 Sep 16
Ultrasound Detects Central Line Placement and Postprocedure Pneumothorax
SUMMARY AND COMMENT
Chest x-ray missed 2 of 4 pneumothoraces and 1 of 25 misplaced catheter tips that were detected by bedside ultrasound.
Reviewing:
Vezzani A et al., Crit Care Med 2009 Oct 12
Induced Hypothermia After VF Cardiac Arrest Improves Outcomes
SUMMARY AND COMMENT
Hypothermia led to significantly better survival rates and neurological outcomes in patients with ventricular fibrillation but not in those with other initial rhythms.
Reviewing:
Don CW et al., Crit Care Med 2009 Sep 16
N95 Respirators or Surgical Mask for Protection from Influenza?
SUMMARY AND COMMENT
By current knowledge, a surgical mask is sufficient. Save N95 respirators for TB and other aerosol-transmitted diseases.
Reviewing:
Gralton J and McLaws M-L., Crit Care Med 2009 Sep 1
Glucose Control in Type 2 Diabetes: Review of Cardiovascular Outcomes
SUMMARY AND COMMENT
Intensive control led to fewer nonfatal MIs but no change in 5-year all-cause mortality.
Reviewing:
Kelly TN et al., Ann Intern Med 2009 Sep 15; 151:394
Peramivir for Treatment of 2009 H1N1 Influenza
DRUG WATCH
Responding to a CDC request, the FDA authorized the emergency use of this investigational agent in critically ill patients.
Reviewing:
Food and Drug Administration (FDA)., 2009 Oct 24
Centers for Disease Control and Prevention (CDC)., 2009 Oct 23
Birnkrant D and Cox E., N Engl J Med 2009 Nov 2