Palliative Sedation to Alleviate Intractable Distress of the Dying Patient
FEATURE
November 16, 2009
Stephanie Grossman, MD, FHM, FAAPM
A review of treatment options
Reviewing:
Quill TE et al., Ann Intern Med 2009 Sep 15; 151:421
ARBITER 6-HALTS: A Surprise Knockout
SUMMARY AND COMMENT
Niacin's clear win over ezetimibe as an adjunct to statin therapy challenges assumptions about lipid management.
Reviewing:
Taylor AJ et al., N Engl J Med 2009 Nov 16
Immediate vs. Delayed ICU Admission for Patients with CAP
SUMMARY AND COMMENT
Direct admission to the ICU is associated with lower mortality and shorter hospital stay.
Reviewing:
Renaud B et al., Crit Care Med 2009 Nov; 37:2867
ECMO for Patients with 2009 H1N1 Influenza and ARDS
SUMMARY AND COMMENT
In a study from New Zealand and Australia, ECMO was used largely in young adults, most of whom had good outcomes.
Reviewing:
Davies A et al for the Australia and New Zealand Extracorporeal Membrane Oxygenation., JAMA 2009 Nov 4; 302:1888
Trends in ED Wait Times by Triage Class
SUMMARY AND COMMENT
Increasingly, EDs fail to provide care within the target time for their sickest patients.
Reviewing:
Horwitz LI and Bradley EH., Arch Intern Med 2009 Nov 9; 169:1857
Hsia RY and Tabas JA., Arch Intern Med 2009 Nov 9; 169:1836
Prevention of Flu Transmission in Households
SUMMARY AND COMMENT
Hand hygiene and face masks can help prevent the spread of influenza.
Reviewing:
Cowling BJ et al., Ann Intern Med 2009 Oct 6; 151:437
Mortality in Dialysis Patients
SUMMARY AND COMMENT
Risk was elevated for both cardiovascular and noncardiovascular causes.
Reviewing:
de Jager DJ et al., JAMA 2009 Oct 28; 302:1782
Revascularization Is Ineffective for Atherosclerotic Renal Artery Stenosis
SUMMARY AND COMMENT
This procedure conferred substantial risk without clinical benefit.
Reviewing:
The ASTRAL Investigators., N Engl J Med 2009 Nov 12; 361:1953
When Biology Meets Personal Choices
SUMMARY AND COMMENT
Risks for ischemic stroke and myocardial infarction were substantially higher in women with lupus anticoagulant who smoked or used oral contraceptives.
Reviewing:
Urbanus RT et al., Lancet Neurol 2009 Nov; 8:998
Pneumococcal DNA Load in CAP
SUMMARY AND COMMENT
The Streptococcus pneumoniae DNA load in blood may have both diagnostic and therapeutic implications.
Reviewing:
Peters RPH et al., J Clin Microbiol 2009 Oct; 47:3308