NSAIDs, Acetaminophen, and GI Events
Gastroenterology
Summary and Comment Subscription required
Risk for GI bleeding may be higher with the two drugs combined than with either drug alone.
A "Troponin" for the Kidney?
Emergency Medicine
Summary and Comment Subscription required
Moving beyond serum creatinine
Direct Admission to the Cath Lab for Patients with STEMI
Emergency Medicine
Summary and Comment Subscription required
Bypassing the ED might be an effective strategy to shorten time to PCI.
Metronidazole vs. Vancomycin for CDAD
Infectious Diseases
Summary and Comment Subscription required
After 5 days of therapy, resolution of diarrhea and suppression of C. difficile to undetectable levels were significantly more likely with vancomycin than with metronidazole.
By Neil M. Ampel, MD
June 25, 2008
Covering:
Al-Nassir WN et al., Clin Infect Dis 2008 Jul 1; 47:56
Nutritional Support and Mortality in Patients with Sepsis
Infectious Diseases
Summary and Comment Subscription required
Researchers in Germany identified enteral nutrition as a significant independent predictor for reduced mortality in patients with sepsis.
By Thomas Glück, MD
June 25, 2008
Covering:
Elke G et al., Crit Care Med 2008 Jun; 36:1762
Marik PE., Crit Care Med 2008 Jun; 36:1964
MRSA in Healthcare Workers
Infectious Diseases
Summary and Comment Free
Two studies showed a high prevalence of MRSA colonization among emergency department healthcare workers.
By Richard T. Ellison III, MD
June 25, 2008
Covering:
Bisaga A et al., Ann Emerg Med 2008 Apr 25
Suffoletto BP et al., Ann Emerg Med 2008 Apr 25
Rivaroxaban for Thromboprophylaxis After Joint Replacement
Oncology and Hematology
Summary and Comment Free
In two large, randomized studies, rivaroxaban was superior to enoxaparin in preventing venous thrombosis.
By David Green, MD, PhD
June 25, 2008
Covering:
Eriksson BI et al., N Engl J Med 2008 Jun 26; 358:2765
Lassen MR et al., N Engl J Med 2008 Jun 26; 358:2776
Aggressive Statin Treatment After Bypass Surgery
Cardiology
Summary and Comment Subscription required
In a retrospective analysis of patients who had previously undergone CABG, a higher dose of atorvastatin was associated with better outcomes than a lower dose.
Bare-Metal and Drug-Eluting Stents: Whats the Bottom Line?
Cardiology
Summary and Comment Free
Results of a retrospective study of Medicare patients suggest that, on balance, drug-eluting stents have improved outcomes.
High-Dose Amphotericin B for Cryptococcal Meningitis
HIV/AIDS
Summary and Comment Free
High-dose AmB is already the standard of care in many clinics, but its use is now supported by data from a randomized trial.
By Judith Feinberg, MD
June 23, 2008
Covering:
Bicanic T et al., Clin Infect Dis 2008 Jul 1; 47:123